Journal: Frontiers in Pharmacology
Article Title: Osteoprotective Effects in Postmenopausal Osteoporosis Rat Model: Oral Tocotrienol vs. Intraosseous Injection of Tocotrienol-Poly Lactic-Co-Glycolic Acid Combination
doi: 10.3389/fphar.2021.706747
Figure Lengend Snippet: DEXA Parameters (pre- and posttreatment). (A) Bone mineral content of the tibial bone. (B) Bone mineral density of the tibial bone. SHAM, sham-operated group; OVX, ovariectomized control group; OVX + ESTO, ovariectomized + oral estrogen; OVX + TTO, ovariectomized + daily oral tocotrienol; OVX + TTL, ovariectomized + IO injection of tocotrienol + PLGA. *Significant difference ( p < 0.05) when compared before and after treatment. a Significant difference ( p < 0.05) when compared with the ovariectomized control group (OVX). The data were expressed as mean + SEM.
Article Snippet: Prior to the scanning procedure, a Hologic Discovery W DEXA machine (Hologic, Inc., MA, United States) was calibrated using “Small Animal Phantom.” The DEXA analysis was performed using the APEX TM software.
Techniques: Control, Injection